These findings highlight the need to strengthen MAYV surveillance in the region and showcase how modeling can improve interpretation of cross-reacting assays.
This study described a large-scale representative ZIKV seroprevalence study in South America from the recent 2015–2016 Zika epidemic. The findings reveal that the majority of the population remains susceptible to ZIKV, which could potentially allow future reintroductions of the virus.
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